49ers vs. Patriots 2024 Prediction, Odds, Expert Pick

The San Francisco 49ers (1-2) are considered favorites (-10.5) according to nan bookmakers up of their crippled against nan New England Patriots (1-2) connected September 29, 2024, starting astatine 4:05 p.m. ET, airing connected FOX. The matchup has an over/under of 40.5 points.

Keep upward alongside nan 2024 NFL season connected FOX Sports.

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49ers vs. Patriots Odds & Betting Lines

49ers vs. Patriots Prediction & Pick

• Pick ATS: Pick Em 
• Pick OU: Under (40.5) 
• Prediction: 49ers 25 - Patriots 15

How to Watch San Francisco vs. New England

• Game Date: Sunday, September 29, 2024
• Time: 4:05 p.m. ET
• Venue: Levi's Stadium
• Location: Santa Clara, California
• TV: Watch connected FOX
• Live Boxscore: FOX Sports

Pick by FOX Sports Betting Analyst Chris Fallica:

Last week’s nonaccomplishment astatine nan Rams was atrocious and inexcusable for nan Niners, moreover alongside each nan injuries. To rustle a two-TD lead against a squad alongside arsenic galore cardinal injuries arsenic nan Rams conscionable can't happen. Fortunately, nan Niners get 1 of nan worst teams successful nan convention astatine location arsenic a get-right spot. The Patriots O-Line against nan Jets was downright atrocious and I can't spot it getting overmuch amended here. S.F. gets upward early and rolls to a blowout win. 

PICK: 49ers (-10.5) to win by much than 10.5 points

Read More NFL Predictions For This Week

49ers vs. Patriots Recent Matchups

• Over their past 4 meetings, New England has 3 wins against San Francisco.
• San Francisco has been outscored by 29 points successful its past 4 tilts against New England.

San Francisco Betting Info

• This annum San Francisco has 1 win against nan spread.
• San Francisco games this annum person eclipsed nan over/under 2 times successful 3 opportunities (66.7%).
• When playing arsenic nan moneyline favorite, nan 49ers are 1-2, earning a triumph 33.3% of nan time.
• Looking astatine this contest's moneyline, nan 49ers' implied win probability is 85.7%.

49ers Stats

San Francisco's Key Players

Offense

• Brock Purdy ranks 3rd successful nan NFL alongside 842 passing yards successful 3 games this year, averaging 280.7 per crippled alongside a 72.6% completion percent and 4 touchdowns (10th successful nan NFL) against 1 interception.
• He has tacked connected 64 rushing yards (21.3 per game) lacking a touchdown connected nan ground.
• Jordan Mason's rushing statline this play includes 324 yards (second successful nan NFL) and 2 TDs. He is averaging 108.0 yards per crippled and 4.8 per effort (16th successful nan NFL).
• In nan passing game, Jauan Jennings, has racked upward 276 receiving yards (fifth successful nan NFL) and 3 touchdowns (first successful nan NFL) aft catching 18 balls (10th successful nan NFL) connected 21 targets. Per game, he's averaging 92.0 yards and 6.0 receptions successful 3 games.
• Deebo Samuel has 13 receptions for 164 yards and zero touchdowns. He's been targeted 19 times successful nan passing game, and averages 6.5 receptions and 82.0 yards successful 2 games played.

Defense

• On nan protect side, Fred Warner has 20 tackles, 1.0 TFL, 1 sack, and 1 interception successful 2024. His tackle full leads nan 49ers.
• Nick Bosa has 9 tackles, 3.0 TFL, and 2 sacks.
• This season, Isaac Yiadom has put upward 13 tackles.
• So acold this season, Charvarius Ward has 13 tackles.

New England Betting Info

• New England has put jointly a grounds of 2-1-0 against nan dispersed this season.
• Games involving New England has deed nan complete erstwhile this year.
• This season, nan Patriots person won 1 retired of nan 3 games successful that they've been nan underdog.
• The Patriots person a 18.5% chance to win this crippled based connected nan implied probability of nan moneyline.

Patriots Stats

New England's Key Players

Offense

• Rhamondre Stevenson averages 74.7 rushing yards per crippled this annum (224 full yards), during scoring 2 rushing touchdowns.
• Jacoby Brissett has 368 passing yards, 1 touchdown and zero interceptions. His completion percent is 60.9% and he averages 122.7 yards per crippled and 5.3 per attempt.
• He has besides added 38 rushing yards (third connected nan Patriots), alongside zero touchdowns connected nan crushed (averaging 12.7 yards per crippled and 4.2 per carry).
• So acold this play done 3 games, Antonio Gibson has racked upward 143 rushing yards (second connected nan Patriots), but has not scored a rushing touchdown. He averages 47.7 yards per crippled and 6.2 per effort (third successful nan NFL).
• Hunter Henry has 12 catches for 136 yards lacking a receiving touchdown. He averages 4.0 yards per crippled done 3 games and has been targeted 18 times.

Defense

• Keion White's 2024 showing includes 17 tackles, 3.0 TFL, and 4 sacks done 3 games. He is 2nd connected nan Patriots successful tackles.
• Kyle Dugger has 16 tackles, 3.0 TFL, and 1 sack. He is 4th connected nan Patriots successful tackles.
• Jonathan Jones has 18 tackles successful nan 2024 campaign. He leads nan Patriots successful tackles.
• Jahlani Tavai has 17 tackles, 2.0 TFL, and 1 walk defended.

FOX Sports created this communicative utilizing exertion provided by Data Skrive and information from Sportradar.

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